Wasps fly-half Andy Goode was the hero as his virtuoso performance condemned his former side Leicester to a 22-12 defeat at Adams Park.
Goode kicked 17 points including two crucial drop goals in the second half when his side were under pressure and before the interval it was his quick thinking that created the only try of the game for Christian Wade.
The game was fiercely contested throughout but fell far short of last season's corresponding fixture when Wasps won a classic game 35-29.
Wasps were still deserved winners. Apart from Goode's decisive contribution they showed more creativity with Elliot Daly and Joe Simpson, their most enterprising runners.
Leicester had too many absentees and their replacements were not up to the task. Their pack was competitive with Thomas Waldrom producing a few of his trademark bursts but Owen Williams, despite kicking all his side's points, had a miserable afternoon at fly-half, failing to exercise any control in marked contrast to the efforts of Goode.
Newcastle claimed their third Premiership win of the season as they edged out London Irish in a hard-fought game at Kingston Park.
There was little free-flowing scoring on display as a lacklustre, error-strewn game was saved only by the late drama of an Adam Powell try for Newcastle and a nervy fight to the finish for the home side in the 13-11 victory.
Irish openside Ofisa Treviranus scored the only other try in what was a scrappy match littered with handling errors by two sides near the bottom of the table.