The home side chose to bat first having won the toss but lost Chris Gibirdi (5) early in the innings.
Nick Marsden joined Ben Ward at the crease and the pair opted for the cautious approach which had served them well at White Coppice last time out. Marsden (23) played some excellent shots down the ground until he was out caught at long-off.
Mawdesley were it a decent position at 72-2 with 20 overs remaining but that quickly became 85-6 as the dismissal of Ward for 30 prompted a flurry of middle order wickets.
Then Dave Whiteley used all his experience and bating prowess to dig his side out of a hole. Supported by David Wilson (13), Whiteley was able to work the ball into the gaps whilst finding the boundary with any loose deliveries to finish on 40 not out as the innings closed with Mawdesley 137-8.
Nathan Trengove was injured in the warm-up and couldn’t bowl, but Gibirdi stepped up to the plate. Bowling with pace and accuracy, he castled Paul Goodwin and went for a miserly four runs from his six overs.
Visiting skipper Ashley Billington hit 37 to keep his side in the game until Neil O’Malley removed him and five others during a 15.2 over spell which took the game away from Penwortham.
Some lower order resistance from Nathan Walmsley (14) and Ian Dagger (13) delayed the celebrations but left-arm twirler O’Malley sealed maximum points for Mawdesley when he had Dagger excellently caught by Matt Watkinson at slip.
The win takes Mawdesely up to fifth in Division One, just seven points behind leaders Longridge.
Mawdesley 2nd XI got back to winning ways away at BAC/EE Preston 3rd XI thanks to a 26-run victory.
Jay Bethell opted to make first use of the batting track and Brian Parr and Martin Lewis got them off to a fine start. But a run-out sparked a collapse and only Parr (40) was able to make a significant contribution.
Mawdesley’s 126-8 was probably a little below par but the opening bowlers quickly set about making amends. Josh Adamson and Louis Rothwell bowled at a lively pace which was too much for most of the BAC/EE batsmen.
Rothwell claimed 3-17 from his opening spell.
Roy Thompson came into the bowling attack and picked up 4-21 with his wrist spin as the hosts were bowled out for 100 in the 43rd over.
The 2nd XI sit seven points clear at the top of Division Six having claimed five victories from the opening seven fixtures of the season.
The 1st XI were in action again on Sunday but were knocked out of the Meyler Cup by Premier Division side Fulwood & Broughton.
The home side amassed a total of 233-7 from their 40 overs thanks to excellent knocks by Marcus Mollinga (70) and Charlie Rossiter (47).
In reply, Mawdesley set off at the required rate and were still in the game at drinks with the score 100-3. However, a flurry of wickets shortly afterwards dismissed any hopes of a cup upset. Number 11 O’Malley (45*) had some fun but the chase fell 34 runs short.